Which viral infection is most likely responsible for symptoms of malaise, rash, and joint pain in a healthy young nurse?

The symptoms of malaise, rash, and joint pain are commonly associated with Parvovirus B19 infection, particularly in adults. This virus typically causes a condition known as "fifth disease" or erythema infectiosum, which is usually mild in children but can lead to more significant symptoms in adults. The hallmark of Parvovirus B19 infection includes a "slapped cheek" rash in children, but in adults, it can present as a rash along with joint pain and general malaise, making it a likely cause for the symptoms described in this case.

In a healthy young adult, like the nurse mentioned, Parvovirus B19 can trigger synovitis (inflammation of the joints) leading to the associated joint pain. The combination of rash and joint symptoms makes this viral infection the most fitting option among the choices provided.

Other viral infections listed, while capable of causing diverse symptoms, do not typically present with this specific combination of malaise, rash, and joint pain in healthy individuals. For example, Rubella can cause a rash and mild joint pain but is less commonly associated with malaise in adults. Cytomegalovirus can lead to a variety of symptoms but is more often associated with immunocompromised