Which statement concerning NSAIDs is accurate?

NSAIDs, or nonsteroidal anti-inflammatory drugs, are commonly used for pain relief and inflammation reduction. However, they can have significant effects on renal function and liver health. The accurate statement is that NSAIDs should be avoided in patients with renal disease and advanced liver disease. This is because NSAIDs can impair kidney function and may exacerbate existing renal conditions. In patients with compromised liver function, NSAIDs can increase the risk of liver toxicity and further complicate the management of liver disease.

Understanding the implications of NSAID use in these populations is critical for safe prescribing practices. While NSAIDs are effective analgesics, caution must be exercised when considering their use in patients with these underlying health issues to prevent additional complications. This highlights the importance of evaluating overall patient health and making informed decisions regarding medication use.