What symptom is commonly associated with opioid use in terminally ill patients?

Constipation is a well-known and common side effect of opioid use, particularly in terminally ill patients. Opioids work by binding to specific receptors in the brain and gastrointestinal tract, which slows down intestinal motility and reduces the frequency of bowel movements. This effect can lead to constipated bowel habits, causing discomfort and complicating the patient's overall care and quality of life. Given that many terminally ill patients are already dealing with multiple symptoms and medication regimens, managing constipation becomes an important aspect of their care.

While nausea, weight loss, and anxiety can also occur in terminally ill patients, they are not universally caused by opioid use and might stem from various other underlying conditions or treatments. Hence, constipation stands out as a direct and notable consequence of opioid therapy in this patient population.